COL18A1 antibody
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Name
COL18A1 antibody
Category
Primary Antibodies
Provider
FineTest
Reference
FNab02762
Tested Applications
ELISA, WB, IHC
Description
Endostatin is a naturally-occurring 20-kDa C-terminal fragment derived from COL18A1(also named as KNO). It is reported to serve as an anti-angiogenic agent, similar to angiostatin and thrombospondin. It potently inhibits endothelial cell proliferation and inhibits endothelial cell angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling. Endostatin is a broad spectrum angiogenesis inhibitor and may interfere with the pro-angiogenic action of growth factors such as basic fibroblast growth factor(bFGF/FGF-2) and vascular endothelial growth factor(VEGF).
Documentos del producto
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | collagen, type XVIII, alpha 1 (COL18A1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:200-1:1000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 19 kDa, 27 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P39060 |
| Alias | Collagen alpha-1(XVIII) chain,Endostatin,Non-collagenous domain 1 (NC1),COL18A1 |
| Background | Antibody anti-COL18A1 |
| Status | RUO |
| Note | Mol. Weight 19 kDa, 27 kDa |
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