CORO2B antibody
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935106861
info@markelab.com
name
CORO2B antibody
category
Primary Antibodies
provider
FineTest
reference
FNab01884
tested applications
ELISA, WB, IHC
Description
May play a role in the reorganization of neuronal actin structure.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | coronin, actin binding protein, 2B (CORO2B) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 54 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9UQ03 |
| Gene ID | 10391 |
| Alias | CLIPINC,KIAA0925,Protein FC96,Coronin-like protein C,Clipin-C,Coronin-2B |
| Background | Antibody anti-CORO2B |
| Status | RUO |
| Note | Mol. Weight 54 kDa |
Descripción
Coronin 2B (CORO2B) is another member of the coronin protein family, and it shares similarities with CORO2A in its role of regulating actin dynamics. CORO2B is particularly important in the context of immune cells, such as macrophages, where it helps in processes like phagocytosis, cell migration, and the maintenance of actin cytoskeleton integrity. It also contributes to the regulation of immune responses and is involved in signaling pathways that control the activity of immune cells. In addition to its role in immune function, CORO2B has also been found to influence cell signaling in other tissues, including neurons, where it impacts processes related to cell movement and plasticity. Dysregulation of CORO2B can lead to immune deficiencies and other pathologies related to actin regulation.
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