anti- CBLB antibody
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935106861
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name
anti- CBLB antibody
category
Primary Antibodies
provider
FineTest
reference
FNab01318
tested applications
ELISA, WB, IHC
Description
CBLB (Cbl proto-oncogene B, E3 ubiquitin protein ligase) is a protein-coding gene. Diseases associated with CBLB include cannabis dependence. GO annotations related to this gene include signal transducer activity and calcium ion binding. An important paralog of this gene is CBLC.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Cas-Br-M (murine) ecotropic retroviral transforming sequence b |
| Host | Rabbit |
| Reactivity | human,mouse |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 110 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q13191 |
| Gene ID | 868 |
| Alias | CBL-B,CBLB,Cbl-b, RNF56, ADMIO3, Nbla00127 |
| Background | Antibody anti-CBLB |
| Status | RUO |
| Note | This product is for research use only. |
Descripción
CBLB, another member of the CBL family, shares a similar function to CBL in ubiquitinating target proteins, but it has its unique set of substrates and regulatory roles. CBLB primarily regulates immune cell signaling, particularly in T and B cells, by modulating receptor signaling pathways involved in immune responses. It is involved in the regulation of T-cell receptor (TCR) signaling, and its activity helps in controlling the activation threshold of immune cells. Similar to CBL, CBLB can influence the stability of receptors and other signaling molecules by mediating their degradation. Altered expression or mutations in CBLB can affect immune responses, and it has been linked to autoimmune diseases and immune deficiencies.
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anti- CBLB antibody
CBLB (Cbl proto-oncogene B, E3 ubiquitin protein ligase) is a protein-coding gene. Diseases associated with CBLB include cannabis dependence. GO annotations related to this gene include signal transducer activity and calcium ion binding. An important paralog of this gene is CBLC.
Ver Producto