BTK antibody
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935106861
info@markelab.com
name
BTK antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00980
tested applications
ELISA, WB, IHC, IF
Description
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Bruton agammaglobulinemia tyrosine kinase (BTK) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 70-76 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q06187 |
| Gene ID | 695 |
| Alias | Tyrosine-protein kinase BTK,Agammaglobulinemia tyrosine kinase (ATK),B-cell progenitor kinase (BPK),Bruton tyrosine kinase,BTK,AGMX1,ATK,BPK |
| Background | Antibody anti-BTK |
| Status | RUO |
| Note | Mol. Weight 70-76 kDa |
Descripción
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The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
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