Phospho-BTK (Tyr223) Antibody
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935106861
info@markelab.com
name
Phospho-BTK (Tyr223) Antibody
category
Primary Antibodies
provider
FineTest
reference
FNab09846
tested applications
ELISA, WB
Description
Defects in the Bruton tyrosine kinase(BTK) gene cause Agammaglobulinemia. Agammaglobulinemia is an X-linked immunodeficiency characterized by failure to produce mature B lymphocyte cells and associated with a failure of Ig heavy chain rearrangement.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | peptide (Phospho-BTK (Tyr223)) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 80 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at-20 °C. Stable for 12 months from date of receipt |
| UniProt ID | Q06187 |
| Alias | Tyrosine-protein kinase BTK,Agammaglobulinemia tyrosine kinase (ATK),B-cell progenitor kinase (BPK),Bruton tyrosine kinase,BTK,AGMX1,ATK,BPK |
| Background | Antibody anti-BTK |
| Status | RUO |
| Note | Mol. Weight 80 kDa |
Descripción
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BTK antibody
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
Ver ProductoPhospho-BTK (Tyr223) Antibody
Defects in the Bruton tyrosine kinase(BTK) gene cause Agammaglobulinemia. Agammaglobulinemia is an X-linked immunodeficiency characterized by failure to produce mature B lymphocyte cells and associated with a failure of Ig heavy chain rearrangement.
Ver Producto