APOA2 antibody
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
APOA2 antibody
Category
Primary Antibodies
Provider
FineTest
Reference
FNab00507
Tested Applications
ELISA, WB, IHC
Description
The predicted MW of ApoA2 is 11 kDa, while the mature form is smaller (7-10 kDa) since the signal peptide was cleaved. In humans, most of circulating apoA2 exist as dimer.
Documentos del producto
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | apolipoprotein A-II (APOA2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:50-1:500 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 15 kDa,11 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P02652 |
| Gene ID | 336 |
| Alias | APOA2, Apo-AII, ApoA-II, apoAII, Apolipoprotein A2,APO A2,APO-A2,Apolipoprotein A-II |
| Background | Antibody anti-APOA2 |
| Status | RUO |
| Note | Mol. Weight 15 kDa, 11 kDa |
Background
APOA2 is the second most abundant protein in HDL particles and is involved in stabilizing HDL structure and influencing cholesterol metabolism. It plays a role in modulating HDL remodeling, impacting the balance between cholesterol efflux and lipid delivery. APOA2 has a controversial role in cardiovascular health, with studies showing both pro-atherogenic and anti-atherogenic effects depending on genetic variants and lipid context. Elevated APOA2 levels have been linked to obesity, insulin resistance, and metabolic syndrome, while deficiencies can impair HDL stability and function. APOA2 interacts with enzymes like hepatic lipase and proteins such as CETP (cholesteryl ester transfer protein), which regulate lipid exchange and metabolism. Its dual role in lipid homeostasis and metabolic health highlights its significance in cardiovascular disease and metabolic disorders.
Productos relacionados
Apolipoprotein A-II (Apo AII) Antibody
Apo AII Antibody is a Goat polyclonal antibody for lipoproteins against Apo AII.…
Ver producto
Apolipoprotein A-II (APOA2) Antibody
May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism.…
Ver producto
Human Apolipoprotein A2 (APOA2) Protein
Human Apolipoprotein A2 (APOA2) is a recombinant Human protein expressed in E. coli.…
Ver producto