APLP1 antibody
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Description
This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | amyloid beta (A4) precursor-like protein 1 (APLP1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 70 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P51693 |
| Gene ID | 333 |
| Alias | Amyloid beta precursor like protein 1,Amyloid beta (A4) precursor-like protein 1,Amyloid-like protein 1 (APLP, APLP-1),C30,APLP1 |
| Background | Antibody anti-APLP1 |
| Status | RUO |
| Note | Mol. Weight 70 kDa |
Descripción
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