ANP32A antibody

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935106861
info@markelab.com
name
ANP32A antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00445
tested applications
ELISA, WB, IHC, IF
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A (ANP32A) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 28 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB, IHC, IF |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
UniProt ID | P39687 |
Gene ID | 8125 |
Alias | ANP32A,C15orf1,LANP |
Background | Antibody anti-ANP32A |
Status | RUO |
Note | Mol. Weight 28 kDa |
ANP32A is a multifunctional nuclear phosphoprotein involved in chromatin remodeling, RNA splicing, and cell cycle regulation. ANP32A interacts with histone acetyltransferases (HATs) and histone deacetylases (HDACs), playing a critical role in regulating gene expression and epigenetic modifications. It is also involved in apoptosis and cellular stress responses, where it mediates pathways controlling cell survival and death. ANP32A is implicated in tumorigenesis, acting as either a tumor suppressor or facilitator depending on cellular context. Additionally, it has roles in influenza viral replication by interacting with viral polymerases, making it a key factor in host-virus interactions. Its diverse regulatory functions highlight its importance in nuclear processes and disease mechanisms.
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