Acidic Leucine-Rich Nuclear Phosphoprotein 32 Family Member A (ANP32A) Antibody

Este producto es parte de ANP32 - Acidic leucine-rich nuclear phosphoprotein 32 family
Acidic Leucine-Rich Nuclear Phosphoprotein 32 Family Member A (ANP32A) Antibody
195€ (20 µl)

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Name
Acidic Leucine-Rich Nuclear Phosphoprotein 32 Family Member A (ANP32A) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx004416
Tested Applications
ELISA, WB, IHC

Description

ANP32A Antibody is a Rabbit Polyclonal antibody against ANP32A.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
Target: Acidic Leucine-Rich Nuclear Phosphoprotein 32 Family Member A (ANP32A)
Immunogen: Recombinant protein corresponding to ANP32A. The exact sequence is proprietary.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Assay Type
Concentration: > 0.2 mg/ml
Recommended Dilution
ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
Calculated MW: 29 kDa  Observed MW: 28 kDa
Purification
Purified by affinity chromatography.
Size 1
20 µl
Size 2
100 µl
Size 3
2 × 100 µl
Form
Liquid
Tested Applications
ELISA, WB, IHC
Buffer
PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P39687
Gene ID
8125
NCBI Accession
NP_006296.1
Alias
ANP32A,C15orf1,LANP
Background
Antibody anti-ANP32A
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Background

ANP32A is a multifunctional nuclear phosphoprotein involved in chromatin remodeling, RNA splicing, and cell cycle regulation. ANP32A interacts with histone acetyltransferases (HATs) and histone deacetylases (HDACs), playing a critical role in regulating gene expression and epigenetic modifications. It is also involved in apoptosis and cellular stress responses, where it mediates pathways controlling cell survival and death. ANP32A is implicated in tumorigenesis, acting as either a tumor suppressor or facilitator depending on cellular context. Additionally, it has roles in influenza viral replication by interacting with viral polymerases, making it a key factor in host-virus interactions. Its diverse regulatory functions highlight its importance in nuclear processes and disease mechanisms.

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