ANXA2 antibody
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935106861
info@markelab.com
name
ANXA2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00430
tested applications
ELISA, IHC, IF, WB
Description
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | annexin A2 (ANXA2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:20 - 1:50 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 38 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC, IF, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P07355 |
| Gene ID | 302 |
| Alias | ANXA2,ANX2,ANX2L4,CAL1H |
| Background | Antibody anti-ANXA2 |
| Status | RUO |
| Note | Mol. Weight 38 kDa |
Descripción
ANXA6 is a calcium-dependent phospholipid-binding protein involved in membrane dynamics, endocytosis, and exocytosis. It is one of the largest annexins and interacts with components of the cytoskeleton and plasma membrane to regulate vesicle trafficking and cholesterol homeostasis. ANXA6 plays a role in calcium signaling, influencing the activation of ion channels and cellular processes such as cell adhesion, migration, and signal transduction. Its expression is elevated in certain cancers, including breast cancer, where it modulates cell proliferation and survival. ANXA6 also participates in immune responses and lipid metabolism, linking its dysregulation to cardiovascular diseases and metabolic disorders. Its versatile functions make it a critical player in maintaining cellular integrity under normal and stressed conditions.
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