ANXA10 antibody
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935106861
info@markelab.com
name
ANXA10 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00427
tested applications
ELISA, WB
Description
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. The function of this gene has not yet been determined.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | annexin A10 (ANXA10) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 37 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9UJ72 |
| Alias | Annexin-10,Annexin-14,ANX14 |
| Background | Antibody anti-ANXA10 |
| Status | RUO |
| Note | Mol. Weight 37 kDa |
Descripción
ANXA10 is a member of the annexin family that binds to calcium and phospholipids to mediate membrane-related processes, including membrane trafficking and signal transduction. ANXA10 expression is largely restricted to the gastrointestinal tract, particularly in the stomach and liver, where it contributes to cell differentiation and epithelial integrity. Dysregulation or loss of ANXA10 expression has been associated with gastric cancer, hepatocellular carcinoma, and other gastrointestinal malignancies, serving as a marker for tumor progression and poor prognosis. Its role in maintaining epithelial cell homeostasis underscores its importance in gastrointestinal health and disease.
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