Amphiphysin(AMPH), a synaptic vesicle-associated protein that is highly concentrated in nerve terminal, is an autoantigen of Stiff-Man syndrome with breast cancer. Amphiphysin contains a N-terminal BAR(Bin1/Amphiphysin/Rv167) domain followed by an endocytosis domain, and a C-terminal SH3 domain. Amphiphysin has been proposed to function as a linker between the clathrin coat and dynamin in the endocytosis of synaptic vesicles. It may also participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types.
Primary Antibodies
polyclonal
human,mouse,rat
amphiphysin
Rabbit
IgG
Unconjugated
liquid
ELISA, WB, IHC, IP
120 kDa
≥95% as determined by SDS-PAGE
Immunogen affinity purified
WB: 1:500-1:5000; IHC: 1:20-1:200; IP: 1:500-1:5000
100µg
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
AMPH
AMPH,AMPH1
This product is for research use only.
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Ver másAmphiphysin(AMPH), a synaptic vesicle-associated protein that is highly concentrated in nerve terminal, is an autoantige...
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