Fructose-bisphosphate aldolase C(ALDOC) reversibly cleaves FBP and F1-P to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate and is strongly expressed in mammalian brain together with ALDOA and is alsopresent in the heart and spleen of some species(PMID:9363598). It is involed in glycolysis as an important enzyme. Phospholipase D2 and inositol 1,4,5-triphosphate interact with ALDOC in signal transduction. Meanwhile, the protein expression of ALDOC has been reported to be regulated in brain tumor, hepatomas, and lung cancer(PMID:21548097).
Primary Antibodies
monoclonal
human
aldolase C, fructose-bisphosphate
Mouse
IgG1
Unconjugated
liquid
ELISA, WB, IHC, IF
39 kDa
≥95% as determined by SDS-PAGE
Protein A+G purification
WB: 1:5000-1:50000; IHC: 1:50-1:500; IF: 1:20-1:200
100µg
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
ALDOC
ALDOC,ALDC
This product is for research use only.
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Ver másFructose-bisphosphate aldolase C(ALDOC) reversibly cleaves FBP and F1-P to glyceraldehyde 3-phosphate and dihydroxyaceto...
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