anti- ALDOB antibody
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935106861
info@markelab.com
name
anti- ALDOB antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00302
tested applications
ELISA, WB, IHC, IF, IP
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | aldolase B, fructose-bisphosphate |
| Host | Rabbit |
| Reactivity | human,mouse,rat |
| Recommended Dilution | WB: 1:500-1:5000; IHC: 1:20-1:200; IP: 1:500-1:5000; IF: 1:10-1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 35 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P05062 |
| Gene ID | 229 |
| Alias | ALDOB,ALDB |
| Background | Antibody anti-ALDOB |
| Status | RUO |
| Note | This product is for research use only. |
ALDOB is a liver-specific isoform of fructose-bisphosphate aldolase that primarily participates in fructose metabolism. It catalyzes the breakdown of fructose-1,6-bisphosphate and fructose-1-phosphate into dihydroxyacetone phosphate and glyceraldehyde, which are intermediates in glycolysis and gluconeogenesis. ALDOB is highly expressed in the liver, kidney, and small intestine. Mutations in ALDOB result in hereditary fructose intolerance (HFI), an autosomal recessive disorder characterized by the toxic accumulation of fructose-1-phosphate, leading to hypoglycemia, hepatomegaly, and renal dysfunction. ALDOB’s critical role in fructose metabolism highlights its importance in dietary sugar processing and maintaining energy balance.
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