AFAP1L2 antibody
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Name
AFAP1L2 antibody
Category
Primary Antibodies
Provider
FineTest
Reference
FNab00194
Tested Applications
ELISA, WB
Description
May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation.
Documentos del producto
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | actin filament associated protein 1-like 2 (AFAP1L2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:200-1:1000; IP: 1:200-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 110 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q8N4X5 |
| Gene ID | 84632 |
| Alias | XB130 |
| Background | Antibody anti-AFAP1L2 |
| Status | RUO |
| Note | Mol. Weight 110 kDa |
Background
Actin Filament Associated Protein 1 Like 2 (AFAP1L2), also known as XB130, is another member of the AFAP family implicated in actin filament dynamics and signal transduction. It functions as an adaptor protein, coordinating interactions between cytoskeletal elements and signaling pathways involved in cell growth, survival, and migration. AFAP1L2 is highly expressed in epithelial tissues and is linked to inflammatory responses and cancer progression. It also plays a role in regulating apoptosis and epithelial-to-mesenchymal transition (EMT), processes critical for tissue remodeling and tumorigenesis.
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