Actin Filament Associated Protein 1 Like 2 (AFAP1L2) Antibody
364€ (100 µg)
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935106861
info@markelab.com
name
Actin Filament Associated Protein 1 Like 2 (AFAP1L2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx230194
tested applications
ELISA, WB
Description
AFAP1L2 Antibody is a Rabbit Polyclonal against AFAP1L2.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Actin Filament Associated Protein 1 Like 2 (AFAP1L2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/200 - 1/1000, IP: 1/200 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8N4X5 |
| Gene ID | 84632 |
| OMIM | 612420 |
| Alias | XB130 |
| Background | Antibody anti-AFAP1L2 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
Actin Filament Associated Protein 1 Like 2 (AFAP1L2), also known as XB130, is another member of the AFAP family implicated in actin filament dynamics and signal transduction. It functions as an adaptor protein, coordinating interactions between cytoskeletal elements and signaling pathways involved in cell growth, survival, and migration. AFAP1L2 is highly expressed in epithelial tissues and is linked to inflammatory responses and cancer progression. It also plays a role in regulating apoptosis and epithelial-to-mesenchymal transition (EMT), processes critical for tissue remodeling and tumorigenesis.
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