Actin Filament-Associated Protein 1-Like 2 (AFAP1L2) Antibody
383.5€ (100 µl)
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Name
Actin Filament-Associated Protein 1-Like 2 (AFAP1L2) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx224343
Tested Applications
ELISA, WB, IHC
Description
AFAP1L2 Antibody is a Mouse Monoclonal against AFAP1L2.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Actin Filament-Associated Protein 1-Like 2 (AFAP1L2) Immunogen: Purified recombinant fragment of human AFAP1L2 (AA: 674-818) expressed in E. coli. |
| Host | Mouse |
| Reactivity | Human |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Observed MW | 89.8 kDa |
| Purification | Purified from ascites by Protein G chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, containing 0.05% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96T88 |
| Gene ID | 29128 |
| OMIM | 607990 |
| Alias | XB130 |
| Background | Antibody anti-AFAP1L2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Actin Filament Associated Protein 1 Like 2 (AFAP1L2), also known as XB130, is another member of the AFAP family implicated in actin filament dynamics and signal transduction. It functions as an adaptor protein, coordinating interactions between cytoskeletal elements and signaling pathways involved in cell growth, survival, and migration. AFAP1L2 is highly expressed in epithelial tissues and is linked to inflammatory responses and cancer progression. It also plays a role in regulating apoptosis and epithelial-to-mesenchymal transition (EMT), processes critical for tissue remodeling and tumorigenesis.
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