ADCY8 antibody
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935106861
info@markelab.com
name
ADCY8 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00158
tested applications
ELISA, WB
Description
This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence(By similarity).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | adenylate cyclase 8(brain) (ADCY8) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:5000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 140 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P40145 |
| Gene ID | 114 |
| Alias | AC8,ADCY3,HBAC1 |
| Background | Antibody anti-ADCY8 |
| Status | RUO |
| Note | Mol. Weight 140 kDa |
Descripción
ADCY8 is a calcium/calmodulin-activated enzyme predominantly expressed in the brain, particularly in regions involved in synaptic plasticity and memory formation. It plays a key role in generating cAMP in response to elevated calcium levels, thereby regulating neuronal excitability and synaptic strength. ADCY8 is involved in processes such as learning, memory, and mood regulation. Dysregulation of ADCY8 has been linked to neurological disorders, including depression and cognitive decline, due to impaired calcium-dependent cAMP signaling.
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