Adenylate Cyclase Type 8 (ADCY8) Antibody
273€ (100 µl)
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name
Adenylate Cyclase Type 8 (ADCY8) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx128939
tested applications
WB
Description
Adenylate Cyclase Type 8 Antibody is a Rabbit Polyclonal against Adenylate Cyclase Type 8.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Adenylate Cyclase Type 8 (ADCY8) Immunogen: abx167169 - Recombinant ADCY8 (His915-Pro1251) expressed in E. coli |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC (Predicted): 5-20 µg/ml, IF/ICC (Predicted): 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P40145 |
| Gene ID | 114 |
| OMIM | 103070 |
| Alias | AC8,ADCY3,HBAC1 |
| Background | Antibody anti-ADCY8 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
ADCY8 is a calcium/calmodulin-activated enzyme predominantly expressed in the brain, particularly in regions involved in synaptic plasticity and memory formation. It plays a key role in generating cAMP in response to elevated calcium levels, thereby regulating neuronal excitability and synaptic strength. ADCY8 is involved in processes such as learning, memory, and mood regulation. Dysregulation of ADCY8 has been linked to neurological disorders, including depression and cognitive decline, due to impaired calcium-dependent cAMP signaling.
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Human Adenylate Cyclase Type 8 (ADCY8) Protein
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