Adenylate Cyclase Type 8 (ADCY8) Antibody
637€ (100 µl)
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Name
Adenylate Cyclase Type 8 (ADCY8) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx110849
Tested Applications
ELISA, WB
Description
Adenylate Cyclase 8 (Brain) Antibody is a Rabbit Polyclonal antibody against Adenylate Cyclase 8 (Brain).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Adenylate Cyclase Type 8 (ADCY8) Immunogen: Human ADCY8. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P40145 |
| Gene ID | 114 |
| OMIM | 103070 |
| Alias | AC8,ADCY3,HBAC1 |
| Background | Antibody anti-ADCY8 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ADCY8 is a calcium/calmodulin-activated enzyme predominantly expressed in the brain, particularly in regions involved in synaptic plasticity and memory formation. It plays a key role in generating cAMP in response to elevated calcium levels, thereby regulating neuronal excitability and synaptic strength. ADCY8 is involved in processes such as learning, memory, and mood regulation. Dysregulation of ADCY8 has been linked to neurological disorders, including depression and cognitive decline, due to impaired calcium-dependent cAMP signaling.
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