Adenylate Cyclase Type 8 (ADCY8) Antibody

Este producto es parte de ADCY - Adenylate Cyclase Type
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637€ (100 µl)

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935106861
info@markelab.com
name
Adenylate Cyclase Type 8 (ADCY8) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx110849
tested applications
ELISA, WB

Description

Adenylate Cyclase 8 (Brain) Antibody is a Rabbit Polyclonal antibody against Adenylate Cyclase 8 (Brain).

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetAdenylate Cyclase Type 8 (ADCY8)
HostRabbit
ReactivityHuman, Mouse, Rat
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationUnconjugated
IsotypeIgG
PurificationAntigen Affinity Chromatography.
Size 1100 µl
FormLiquid
Tested ApplicationsELISA, WB
BufferPBS, pH 7.3, containing 0.02% Sodium Azide and 50% Glycerol.
AvailabilityShipped within 5-10 working days.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDP40145
Gene ID114
OMIM103070
AliasAC8,ADCY3,HBAC1
BackgroundAntibody anti-ADCY8
StatusRUO

Descripción

ADCY8 is a calcium/calmodulin-activated enzyme predominantly expressed in the brain, particularly in regions involved in synaptic plasticity and memory formation. It plays a key role in generating cAMP in response to elevated calcium levels, thereby regulating neuronal excitability and synaptic strength. ADCY8 is involved in processes such as learning, memory, and mood regulation. Dysregulation of ADCY8 has been linked to neurological disorders, including depression and cognitive decline, due to impaired calcium-dependent cAMP signaling.
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