ACTR1B antibody
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935106861
info@markelab.com
name
ACTR1B antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00126
tested applications
ELISA, IHC, IF, WB
Description
Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ARP1 actin-related protein 1 homolog B, centractin beta(yeast) (ACTR1B) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 42 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC, IF, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P42025 |
| Gene ID | 10120 |
| Alias | ACTR1B,ARP1B,CTRN2,PC3,centractin beta |
| Background | Antibody anti-ACTR1B |
| Status | RUO |
| Note | Mol. Weight 42 kDa |
Descripción
ACTR1B is a paralog of ACTR1A and similarly functions as part of the dynactin complex. It stabilizes the interaction between dynein motors and cargo for efficient intracellular transport. Structurally, ACTR1B forms filament-like structures with other dynactin components, closely resembling actin polymers. Its expression is critical for endosomal and lysosomal trafficking, mitotic spindle positioning, and nuclear migration. ACTR1B dysfunction can lead to disruptions in cellular organization and neurological development, underscoring its importance in cytoskeletal dynamics.
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