anti- ACTR1B antibody

Name: anti- ACTR1B antibody
Brand: FineTest
SKU: FNab00126
Availability: OnlineOnly

Este producto es parte de ACTR - Actin related protein

Pida mas información

935106861

info@markelab.com

Precio

Precio a consultar

Antibody anti-ACTR1B

proveedor

FineTest

reference

FNab00126

Tested Applications

ELISA, IHC, IF, WB

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

Descripción

Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome.

Background

ACTR1B is a paralog of ACTR1A and similarly functions as part of the dynactin complex. It stabilizes the interaction between dynein motors and cargo for efficient intracellular transport. Structurally, ACTR1B forms filament-like structures with other dynactin components, closely resembling actin polymers. Its expression is critical for endosomal and lysosomal trafficking, mitotic spindle positioning, and nuclear migration. ACTR1B dysfunction can lead to disruptions in cellular organization and neurological development, underscoring its importance in cytoskeletal dynamics.

Características del producto

clonality

polyclonal

reactivity

human,mouse,rat

immunogen target

ARP1 actin-related protein 1 homolog B, centractin beta(yeast)

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

liquid

tested applications

ELISA, IHC, IF, WB

observerd MW

42 kDa

purity

≥95% as determined by SDS-PAGE

purification

Immunogen affinity purified

recommended dilution

WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

size 1

100µg

storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

or code

ACTR1B

alias

ACTR1B,ARP1B,CTRN2,PC3,centractin beta

uniprot id

https://www.uniprot.org/uniprotkb/P42025

gene id

https://www.ncbi.nlm.nih.gov/gene/10120

note

This product is for research use only.

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