anti- ACTN4 antibody

Descripción

F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein(Probable). Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation(PubMed:15772161). Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions(By similarity). May also function as a transcriptional coactivator, stimulating transcription mediated by the nuclear hormone receptors PPARG and RARA(PubMed:22351778).

Características del producto

clonality

polyclonal

reactivity

human,mouse,rat

immunogen target

actinin, alpha 4

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

liquid

tested applications

ELISA, WB, IHC, IF, IP, FC

observerd MW

105 kDa

purity

≥95% as determined by SDS-PAGE

purification

Immunogen affinity purified

recommended dilution

WB: 1:500-1:5000; IHC: 1:20-1:200; IP: 1:500-1:5000; IF: 1:10-1:100

size 1

100µg

storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

or code

ACTN4

alias

ACTN4,ACTININ-4,FSGS,FSGS1

uniprot id

https://www.uniprot.org/uniprotkb/O43707

gene id

https://www.ncbi.nlm.nih.gov/gene/81

note

This product is for research use only.

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Human ACTN4(Alpha-actinin-4) ELISA Kit

proveedor

FineTest

reference

EH1627

reactivity

human

status

RUO

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