ACSF2 antibody
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935106861
info@markelab.com
name
ACSF2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00105
tested applications
ELISA, WB, IHC
Description
Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA. Has some preference toward medium-chain substrates. Plays a role in adipocyte differentiation.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | acyl-CoA synthetase family member 2 (ACSF2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:200-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 55-70 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q96CM8 |
| Gene ID | 80221 |
| Alias | ACSMW,AVYV493 |
| Background | Antibody anti-ACSF2 |
| Status | RUO |
| Note | Mol. Weight 55-70 kDa |
Descripción
ACSF2 is an acyl-CoA synthetase that plays a pivotal role in the activation of medium-chain fatty acids by converting them into their corresponding acyl-CoA derivatives, facilitating their incorporation into metabolic pathways such as β-oxidation, lipid biosynthesis, and signaling processes. It is predominantly expressed in metabolically active tissues such as the liver and kidney, where it helps maintain energy balance and lipid homeostasis during varying metabolic states. ACSF2 contributes to the formation of bioactive lipids and provides substrates for ATP production, making it integral to intermediary metabolism. Dysregulation of ACSF2 activity has been linked to metabolic disorders, including obesity and fatty acid oxidation deficiencies, where disrupted activation of fatty acids impairs energy production and lipid processing. Its enzymatic specificity underscores its critical role in maintaining cellular metabolic adaptability and systemic lipid regulation.
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