Acyl-CoA Synthetase Family Member 2 (ACSF2) Antibody
292.5€ (80 µl)
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Name
Acyl-CoA Synthetase Family Member 2 (ACSF2) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx034711
Tested Applications
ELISA, WB
Description
Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA. Has some preference toward medium-chain substrates. Plays a role in adipodyte differentiation.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Acyl-CoA Synthetase Family Member 2 (ACSF2) Immunogen: KLH-conjugated synthetic peptide between 587-615 amino acids from the C-terminal region of human ACSF2. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 68.1 kDa |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96CM8 |
| Alias | ACSMW,AVYV493 |
| Background | Antibody anti-ACSF2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ACSF2 is an acyl-CoA synthetase that plays a pivotal role in the activation of medium-chain fatty acids by converting them into their corresponding acyl-CoA derivatives, facilitating their incorporation into metabolic pathways such as β-oxidation, lipid biosynthesis, and signaling processes. It is predominantly expressed in metabolically active tissues such as the liver and kidney, where it helps maintain energy balance and lipid homeostasis during varying metabolic states. ACSF2 contributes to the formation of bioactive lipids and provides substrates for ATP production, making it integral to intermediary metabolism. Dysregulation of ACSF2 activity has been linked to metabolic disorders, including obesity and fatty acid oxidation deficiencies, where disrupted activation of fatty acids impairs energy production and lipid processing. Its enzymatic specificity underscores its critical role in maintaining cellular metabolic adaptability and systemic lipid regulation.
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