ABLIM1 antibody
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935106861
info@markelab.com
name
ABLIM1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00054
tested applications
ELISA, WB, IHC
Description
May act as scaffold protein(By similarity). May play a role in the development of the retina. Has been suggested to play a role in axon guidance.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | actin binding LIM protein 1 (ABLIM1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:5000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 88 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | O14639 |
| Gene ID | 3983 |
| Alias | ABLIM,LIMAB1,LIMATIN,abLIM-1 |
| Background | Antibody anti-ABLIM1 |
| Status | RUO |
| Note | Mol. Weight 88 kDa |
Descripción
ABLIM1 is a cytoskeletal protein that plays a critical role in actin filament organization and cellular structure. It is characterized by the presence of LIM domains, which facilitate protein-protein interactions, and actin-binding domains that enable its association with the cytoskeleton. ABLIM1 is expressed in various tissues, including neurons, where it contributes to the stability and dynamics of the actin cytoskeleton. It plays a key role in processes such as cell shape maintenance, migration, and signal transduction. ABLIM1 also interacts with signaling molecules and transcription factors, influencing pathways involved in neuronal differentiation and synaptic activity. Dysregulation of ABLIM1 expression or function has been associated with cytoskeletal abnormalities and neurological disorders, emphasizing its importance in cellular architecture and neural health.
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