Actin-Binding LIM Protein 1 (ABLIM1) Antibody
260€ (50 µl)
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935106861
info@markelab.com
name
Actin-Binding LIM Protein 1 (ABLIM1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx213135
tested applications
ELISA, WB, IHC
Description
ABLIM1 Antibody is a Rabbit Polyclonal against ABLIM1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Actin-Binding LIM Protein 1 (ABLIM1) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | ELISA: 1/2000 - 1/5000, WB: 1/500 - 1/2000, IHC: 1/15 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O14639 |
| Gene ID | 3983 |
| Alias | ABLIM,LIMAB1,LIMATIN,abLIM-1 |
| Background | Antibody anti-ABLIM1 |
| Status | RUO |
Descripción
ABLIM1 is a cytoskeletal protein that plays a critical role in actin filament organization and cellular structure. It is characterized by the presence of LIM domains, which facilitate protein-protein interactions, and actin-binding domains that enable its association with the cytoskeleton. ABLIM1 is expressed in various tissues, including neurons, where it contributes to the stability and dynamics of the actin cytoskeleton. It plays a key role in processes such as cell shape maintenance, migration, and signal transduction. ABLIM1 also interacts with signaling molecules and transcription factors, influencing pathways involved in neuronal differentiation and synaptic activity. Dysregulation of ABLIM1 expression or function has been associated with cytoskeletal abnormalities and neurological disorders, emphasizing its importance in cellular architecture and neural health.
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