Actin-Binding LIM Protein 1 (ABLIM1) Antibody
357.5€ (100 µg)
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Name
Actin-Binding LIM Protein 1 (ABLIM1) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx037962
Tested Applications
ELISA, WB, IHC
Description
Rabbit Polyclonal against the ABLIM1 protein.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Actin-Binding LIM Protein 1 (ABLIM1) Immunogen: Recombinant fragment corresponding to 142-376 AA of human ABLIM1. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 88 kDa |
| Purification | Purified by Protein A/G column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | ABLIM,LIMAB1,LIMATIN,abLIM-1 |
| Background | Antibody anti-ABLIM1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ABLIM1 is a cytoskeletal protein that plays a critical role in actin filament organization and cellular structure. It is characterized by the presence of LIM domains, which facilitate protein-protein interactions, and actin-binding domains that enable its association with the cytoskeleton. ABLIM1 is expressed in various tissues, including neurons, where it contributes to the stability and dynamics of the actin cytoskeleton. It plays a key role in processes such as cell shape maintenance, migration, and signal transduction. ABLIM1 also interacts with signaling molecules and transcription factors, influencing pathways involved in neuronal differentiation and synaptic activity. Dysregulation of ABLIM1 expression or function has been associated with cytoskeletal abnormalities and neurological disorders, emphasizing its importance in cellular architecture and neural health.
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