Anoctamin-10 (ANO10) Antibody

Product specifications

Primary Antibodies

Anoctamin-10 (ANO10)

Rabbit

Human

Optimal dilutions/concentrations should be determined by the end user.

Polyclonal

Unconjugated

Purified by affinity chromatography using epitope-specific immunogen.

100 µg

Liquid

ELISA, WB

PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.

Shipped within 5-12 working days.

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

No

Q9NW15

55129

ANO10,TMEM16K

Antibody anti-ANO10

RUO

Concentration: 1 mg/ml -

Descripción

ANO10 is a member of the anoctamin family but is distinct from other family members in its function and expression patterns. ANO10 has been implicated in cellular processes such as lipid metabolism, membrane trafficking, and calcium signaling. It is primarily expressed in the nervous system and has been linked to neurodegenerative disorders. Mutations in the ANO10 gene are associated with spinocerebellar ataxia type 10 (SCA10), a progressive neurodegenerative disease characterized by gait imbalance, ataxia, and cerebellar dysfunction. ANO10's role in maintaining neuronal integrity and its involvement in calcium-regulated signaling highlight its importance in the normal function of the central nervous system. Dysregulation or mutation can lead to impaired neuronal signaling and degeneration.

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