Annexin A4 (ANXA4) Antibody
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Description
Annexin A4 (ANXA4) Antibody is a Recombinant Mouse Monoclonal antibody for the detection of Human, Mouse ANXA4.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Annexin A4 (ANXA4) |
| Host | Mouse |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1/1000 - 1/5000, FCM: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Expression | Recombinant |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, FCM |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P09525 |
| Gene ID | 307 |
| NCBI Accession | NP_001144.1, NM_001153.4, NP_001307627.1, NM_001320698.1, NP_001307629.1, NM_001320700.1, NP_001307631.1, NM_001320702.1 |
| OMIM | 106491 |
| Alias | ANXA4,ANX4,Annexin IV,Annexin-4 |
| Background | Antibody anti-ANXA4 |
| Status | RUO |
Descripción
ANXA4 is a calcium-dependent phospholipid-binding protein that participates in membrane repair, ion channel regulation, and signal transduction. It is predominantly expressed in epithelial tissues, particularly in the gastrointestinal tract, kidneys, and lungs, where it regulates cellular processes such as endocytosis and exocytosis. ANXA4 plays a role in calcium signaling, contributing to ion transport and epithelial barrier function. Overexpression of ANXA4 has been observed in cancers such as ovarian, breast, and gastric cancers, where it promotes tumor cell migration and chemoresistance. Its role in maintaining membrane integrity and ion balance highlights its importance in epithelial homeostasis and tumor progression.
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ANXA4 antibody
Annexin IV /placental anticoagulant protein II(ANX4) is a member of the annexin or lipocortin family of calcium-dependent phospholipid binding proteins, and is located at 2p13. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. ANX4 shares 45 to 59% identity with other members and possibly interacts with ATP. ANX4 has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANX4 is almost exclusively expressed in epithelial cells. In western blotting, we get 36 kDa, 39 kDa(with modification), and 60 kDa(an unspecifc band).
Ver ProductoANXA4 antibody
Annexin IV /placental anticoagulant protein II(ANX4) is a member of the annexin or lipocortin family of calcium-dependent phospholipid binding proteins, and is located at 2p13. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. ANX4 shares 45 to 59% identity with other members and possibly interacts with ATP. ANX4 has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANX4 is almost exclusively expressed in epithelial cells. In western blotting, we get 36 kDa, 39 kDa(with modification), and 60 kDa(an unspecifc band).
Ver Producto