Annexin A2 (ANXA2) Antibody
273€ (100 µl)
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935106861
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name
Annexin A2 (ANXA2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx129685
tested applications
WB, IHC, IF/ICC
Description
Annexin A2 Antibody is a Rabbit Polyclonal antibody against Annexin A2.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Annexin A2 (ANXA2) |
| Host | Rabbit |
| Reactivity | Mouse |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P07356 |
| Alias | ANXA2,ANX2,ANX2L4,CAL1H |
| Background | Antibody anti-ANXA2 |
| Status | RUO |
Descripción
ANXA2 is a calcium-dependent phospholipid-binding protein involved in membrane organization, endocytosis, and exocytosis. It plays critical roles in actin cytoskeleton remodeling, facilitating cell adhesion, migration, and vesicular trafficking. ANXA2 is also implicated in angiogenesis and fibrinolysis by serving as a co-receptor for plasminogen and tissue plasminogen activator (tPA), promoting fibrin degradation. Overexpression of ANXA2 has been linked to cancer progression, particularly in breast, lung, and colorectal cancers, where it enhances tumor cell migration, invasion, and metastasis. Additionally, ANXA2 is associated with viral replication, particularly in influenza and hepatitis viruses, making it a therapeutic target for infectious diseases and cancers.
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