Ankyrin Repeat Domain-Containing Protein 44 (ANR44) Antibody
292.5€ (80 µl)
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935106861
info@markelab.com
name
Ankyrin Repeat Domain-Containing Protein 44 (ANR44) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx025905
tested applications
ELISA, WB, IHC
Description
Putative regulatory subunit of protein phospatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Ankyrin Repeat Domain-Containing Protein 44 (ANR44) Immunogen: KLH-conjugated synthetic peptide between 481-510 amino acids from the Central region of human ANR44. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 108 kDa |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8N8A2 |
| Alias | PPP6R1,PP6R1, SAPS1,ANR44 |
| Background | Antibody anti-ANKRD44 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
ANKRD44 is a protein containing ankyrin repeat domains that mediate protein-protein interactions, allowing it to function as a scaffold in cellular signaling pathways. ANKRD44 has been implicated in regulating protein localization, particularly in the context of nuclear and cytoplasmic processes. It may play roles in transcriptional regulation and signal transduction pathways that control cell growth and differentiation. ANKRD44 has also been suggested to interact with components of the ubiquitin-proteasome system (UPS), contributing to protein turnover and homeostasis. Dysregulation of ANKRD44 has been associated with abnormal protein degradation and signaling, which may lead to diseases such as cancer and neurodegenerative disorders.
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