Ankyrin Repeat Domain-Containing Protein 34B (ANKRD34B) Antibody

292.5€ (80 µl)
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935106861
info@markelab.com
name
Ankyrin Repeat Domain-Containing Protein 34B (ANKRD34B) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx026298
tested applications
ELISA, WB, IHC, IF/ICC
Description
ANKRD34B Antibody is a Rabbit Polyclonal antibody against ANKRD34B.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Ankyrin Repeat Domain-Containing Protein 34B (ANKRD34B) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | WB: 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified through a protein A column, followed by peptide affinity purification. |
Size 1 | 80 µl |
Size 2 | 400 µl |
Form | Liquid |
Tested Applications | ELISA, WB, IHC, IF/ICC |
Buffer | PBS containing 0.09% sodium azide. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | A5PLL1 |
Alias | Ankrd34b,Dp58 |
Background | Antibody anti-ANKRD34B |
Status | RUO |
Descripción
ANKRD34B is a protein containing ankyrin repeat domains with structural and functional similarities to ANKRD34A. It is localized in the nucleus and is believed to regulate chromatin structure and transcriptional activity. ANKRD34B likely interacts with other nuclear proteins to coordinate gene expression, particularly during processes such as cell differentiation, DNA repair, and cellular stress responses. ANKRD34B has been implicated in maintaining genomic stability, as its dysregulation may lead to aberrant transcriptional control and genomic instability, a hallmark of cancer. Studies suggest that ANKRD34B may also play roles in developmental regulation and cellular proliferation. Its nuclear localization and chromatin-related functions highlight its significance in cellular homeostasis and disease pathology.
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