Ankyrin Repeat Domain 55 (ANKRD55) Antibody
364€ (100 µg)
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935106861
info@markelab.com
name
Ankyrin Repeat Domain 55 (ANKRD55) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx230418
tested applications
ELISA, WB, IHC, IF/ICC
Description
ANKRD55 Antibody is a Rabbit Polyclonal against ANKRD55.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Ankyrin Repeat Domain 55 (ANKRD55) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/200 - 1/2000, IHC: 1/20 - 1/200, IF/ICC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q3KP44 |
| Gene ID | 79722 |
| OMIM | 615189 |
| Alias | ANKRD55 |
| Background | Antibody anti-ANKRD55 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
ANKRD55 is a protein containing ankyrin repeat domains that mediate protein-protein interactions involved in immune regulation and autoimmune diseases. It has been identified as a susceptibility gene for autoimmune disorders, including multiple sclerosis (MS) and rheumatoid arthritis (RA), where its expression influences inflammatory responses and immune signaling pathways. ANKRD55 is believed to regulate the activity of immune cells, such as T cells, and participate in the modulation of pro-inflammatory cytokine production. Its role in maintaining immune balance highlights its importance in preventing aberrant immune activation and inflammation. Dysregulation or genetic variations in ANKRD55 are associated with increased risk for autoimmune diseases, making it a potential target for therapeutic intervention.
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