Ankyrin Repeat Domain 13D (ANKRD13D) Antibody
377€ (100 µg)
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Name
Ankyrin Repeat Domain 13D (ANKRD13D) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx230409
Tested Applications
ELISA, WB, IHC
Description
ANKRD13D Antibody is a Rabbit Polyclonal against ANKRD13D.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Ankyrin Repeat Domain 13D (ANKRD13D) Immunogen: ankyrin repeat domain 13 family, member D |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: 2 mg/ml |
| Recommended Dilution | WB: 1/200 - 1/1000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 58 kDa |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q6ZTN6 |
| Gene ID | 338692 |
| OMIM | 615126 |
| Alias | ANKRD13D |
| Background | Antibody anti-ANKRD13D |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ANKRD13D is another member of the ANKRD13 family that contains ankyrin repeats and is involved in protein trafficking and ubiquitination. Similar to other ANKRD13 family members, ANKRD13D regulates the stability, localization, and degradation of membrane and cytosolic proteins. It interacts with ubiquitin-binding domains and components of the endosomal system, participating in the selective sorting and recycling of proteins. ANKRD13D is thought to play a role in cellular signaling pathways by modulating the availability and activity of receptors and signaling proteins. Dysregulation of ANKRD13D has been associated with cellular dysfunction, contributing to the development of cancers and disorders involving disrupted proteostasis. Its function in protein quality control and trafficking highlights its significance in regulating cellular signaling and homeostasis.
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