Ankyrin Repeat Domain 13A (ANKRD13A) Antibody
364€ (100 µg)
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935106861
info@markelab.com
name
Ankyrin Repeat Domain 13A (ANKRD13A) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx230406
tested applications
ELISA, WB, IF/ICC
Description
ANKRD13A Antibody is a Rabbit Polyclonal against ANKRD13A.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Ankyrin Repeat Domain 13A (ANKRD13A) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/200 - 1/1000, IF/ICC: 1/10 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IF/ICC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8IZ07 |
| Gene ID | 88455 |
| OMIM | 615123 |
| Alias | ANKRD13A,ANKRD13,KE03 |
| Background | Antibody anti-ANKRD13A |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
ANKRD13A is a member of the ankyrin repeat domain-containing protein family, which is characterized by its ankyrin repeats that mediate protein-protein interactions. ANKRD13A is involved in regulating protein trafficking and ubiquitination, particularly through interactions with proteins targeted for degradation or recycling. It localizes to the endosomal membrane, where it plays a role in controlling the fate of membrane proteins such as receptors and ion channels. ANKRD13A has been shown to interact with ubiquitin-binding domains, suggesting its participation in protein quality control and cellular homeostasis. Dysregulation of ANKRD13A may contribute to altered protein turnover, leading to diseases such as cancer and neurodegenerative disorders, where disrupted trafficking and degradation pathways play critical roles. Its role in protein regulation highlights its importance in maintaining cellular function and integrity.
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