Angiopoietin-Related Protein 1 (ANGPTL1) Antibody (FITC)

Este producto es parte de ANGPTL - Angiopoietin Like
Product Graph
416€ (200 µl)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Angiopoietin-Related Protein 1 (ANGPTL1) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx273737
tested applications
WB, IHC, IF/ICC

Description

Angiopoietin-Related Protein 1 (ANGPTL1) Antibody (FITC) is a Rabbit Polyclonal antibody conjugated to FITC against Angiopoietin-Related Protein 1 (ANGPTL1).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Angiopoietin-Related Protein 1 (ANGPTL1)
Host
Rabbit
Reactivity
Human
Recommended Dilution
WB: 0.5-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
FITC
Isotype
IgG
Purification
Purified by antigen-specific affinity chromatography.
Size 1
200 µl
Size 2
1 ml
Form
Liquid
Tested Applications
WB, IHC, IF/ICC
Buffer
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
Availability
Shipped within 5-15 working days.
Storage
Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
ANG3,ANGPT3,ARP1
Background
Antibody anti-ANGPTL1
Status
RUO

Descripción

ANGPTL1 is a member of the angiopoietin-like (ANGPTL) protein family, which regulates diverse biological processes, including angiogenesis, inflammation, and metabolism, although it does not interact with the Tie2 receptor like classical angiopoietins. ANGPTL1 functions as a tumor suppressor by inhibiting angiogenesis and cancer cell migration. It blocks endothelial cell proliferation and tube formation, reducing blood vessel growth within the tumor microenvironment. ANGPTL1 also regulates cell adhesion and extracellular matrix stability, contributing to tissue homeostasis and integrity. Reduced expression of ANGPTL1 has been observed in several cancers, including lung, liver, and colorectal cancers, where its loss is associated with tumor progression, metastasis, and poor prognosis. ANGPTL1 also plays a role in inhibiting inflammatory responses, linking it to immune regulation and vascular integrity. Its function as an anti-angiogenic and anti-tumor factor highlights ANGPTL1 as a promising therapeutic target for cancer treatment and vascular diseases.

Related Products

EH2632

Human ANGPTL1 (Angiopoietin Like Protein 1) ELISA Kit

Ver Producto
abx037839

Angiopoietin-Related Protein 1 (ANGPTL1) Antibody

Rabbit Polyclonal against the ANGPTL1 protein.

Ver Producto
abx065325

Human Angiopoietin-Related Protein 1 (ANGPTL1) Protein

Human Angiopoietin-Related Protein 1 (ANGPTL1) Protein is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).

Ver Producto