Amyloid Beta A4 Precursor Protein-Binding Family B Member 1-Interacting Protein (APBB1IP) Antibody
364€ (100 µg)
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935106861
info@markelab.com
name
Amyloid Beta A4 Precursor Protein-Binding Family B Member 1-Interacting Protein (APBB1IP) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx237291
tested applications
ELISA, WB, IHC, IP
Description
RIAM Antibody is a Rabbit Polyclonal against RIAM.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Amyloid Beta A4 Precursor Protein-Binding Family B Member 1-Interacting Protein (APBB1IP) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1/500 - 1/2000, IHC: 1/20 - 1/200, IP: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IP |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q7Z5R6 |
| Gene ID | 54518 |
| OMIM | 609036 |
| Alias | APBB1IP, INAG1, PREL1, RARP1, RIAM,Rap1-GTP-interacting adapter molecule |
| Background | Antibody anti-APBB1IP |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
APBB1IP, also known as the Amyloid Beta A4 Precursor Protein-Binding Family B Member 1-Interacting Protein, is a protein involved in cellular signaling, particularly in processes that affect neuronal function. It is known for its role in interacting with amyloid precursor protein (APP), which is associated with Alzheimer’s disease. APBB1IP forms complexes with APP and other signaling proteins, participating in various pathways such as endocytosis, intracellular signaling, and possibly synaptic function. It has been shown to influence processes involved in synaptic plasticity, which are critical for memory and learning. Research into APBB1IP has helped improve our understanding of the molecular mechanisms underlying neurodegenerative diseases, and it is a target of interest in studies aiming to find therapeutic approaches for Alzheimer's disease and related disorders.
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