Alpha-Centractin (ACTR1A) Antibody
169€ (20 µg)
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Name
Alpha-Centractin (ACTR1A) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx301863
Tested Applications
ELISA, WB, IHC
Description
ACTR1A Antibody is a Rabbit Polyclonal against ACTR1A.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Alpha-Centractin (ACTR1A) Immunogen: Recombinant Human Alpha-centractin protein (187-376AA). |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/500 - 1/5000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P61163 |
| Gene ID | 10121 |
| OMIM | 605143 |
| Alias | ACTR1A, ARP1,CTRN1 Arp1A, centractin alpha |
| Background | Antibody anti-ACTR1A |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ACTR1A, also known as ARP1, is a key component of the dynactin complex, a regulator of dynein motor function. Structurally, ACTR1A shares homology with actin and forms a short filament within the dynactin complex. This filament acts as a scaffold for dynein-mediated retrograde transport of vesicles and organelles along microtubules. ACTR1A is highly conserved across eukaryotes, reflecting its essential role in cellular trafficking and mitotic spindle organization. Mutations or dysfunction of ACTR1A impair organelle positioning, leading to developmental and cellular abnormalities.
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