Alpha-Amylase 2B (AMY2B) Antibody

Background

AMY2B is a pancreatic alpha-amylase isozyme that shares structural and functional similarity with AMY2A. It is produced in the pancreas and contributes to the hydrolysis of starch and glycogen into absorbable sugars during digestion in the small intestine. AMY2B, along with AMY2A, ensures efficient breakdown of dietary polysaccharides, supporting energy production and metabolic homeostasis. AMY2B levels are frequently assessed alongside AMY2A to evaluate pancreatic health in clinical settings. Elevated AMY2B levels are associated with acute and chronic pancreatitis, pancreatic trauma, and other gastrointestinal disorders. Genetic variations in AMY2B can impact enzyme activity, influencing carbohydrate metabolism and susceptibility to metabolic diseases such as type 2 diabetes and obesity. While AMY2B primarily functions in digestion, it may also play a role in broader metabolic regulation, underscoring its importance in maintaining pancreatic and systemic energy balance.