Alpha-Amylase 2B (AMY2B) Antibody
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Description
Rabbit Polyclonal against the AMY2B protein.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Alpha-Amylase 2B (AMY2B) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | BC011179 |
| Alias | AMY2,AMY3,HXA |
| Background | Antibody anti-AMY2B |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
AMY2B is a pancreatic alpha-amylase isozyme that shares structural and functional similarity with AMY2A. It is produced in the pancreas and contributes to the hydrolysis of starch and glycogen into absorbable sugars during digestion in the small intestine. AMY2B, along with AMY2A, ensures efficient breakdown of dietary polysaccharides, supporting energy production and metabolic homeostasis. AMY2B levels are frequently assessed alongside AMY2A to evaluate pancreatic health in clinical settings. Elevated AMY2B levels are associated with acute and chronic pancreatitis, pancreatic trauma, and other gastrointestinal disorders. Genetic variations in AMY2B can impact enzyme activity, influencing carbohydrate metabolism and susceptibility to metabolic diseases such as type 2 diabetes and obesity. While AMY2B primarily functions in digestion, it may also play a role in broader metabolic regulation, underscoring its importance in maintaining pancreatic and systemic energy balance.
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