Alpha-2-Macroglobulin (A2M) Antibody
292.5€ (80 µl)
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Name
Alpha-2-Macroglobulin (A2M) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx028308
Tested Applications
ELISA, WB
Description
Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq].
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Alpha-2-Macroglobulin (A2M) Immunogen: KLH-conjugated synthetic peptide between 93-120 amino acids from the N-terminal region of human A2M. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 163 kDa |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P01023 |
| Alias | A2MD,CPAMD5,FWP007,S863-7 |
| Background | Antibody anti-A2M |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Alpha-2-Macroglobulin (A2M) is a large plasma glycoprotein involved in various physiological processes, including immune response regulation, inflammation modulation, and protease inhibition.α-2 macroglobulin (α-2 M) is an inhibitor of matrix metalloproteinases (MMPs). This role occurs when other inhibitors of MMPs, such as tissue inhibitors of matrix metalloproteinases [TIMPs], are deficient.
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