Alpha-2-Macroglobulin (A2M) Antibody
292.5€ (80 µl)
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935106861
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name
Alpha-2-Macroglobulin (A2M) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx028308
tested applications
ELISA, WB
Description
Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq].
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Alpha-2-Macroglobulin (A2M) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P01023 |
| Alias | A2MD,CPAMD5,FWP007,S863-7 |
| Background | Antibody anti-A2M |
| Status | RUO |
Descripción
Alpha-2-Macroglobulin (A2M) is a large plasma glycoprotein involved in various physiological processes, including immune response regulation, inflammation modulation, and protease inhibition.α-2 macroglobulin (α-2 M) is an inhibitor of matrix metalloproteinases (MMPs). This role occurs when other inhibitors of MMPs, such as tissue inhibitors of matrix metalloproteinases [TIMPs], are deficient.
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