Alpha-2-Macroglobulin (A2M) Antibody
312€ (60 µl)
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935106861
info@markelab.com
name
Alpha-2-Macroglobulin (A2M) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx001324
tested applications
IHC
Description
A2M Antibody is a Rabbit Polyclonal antibody against A2M. Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq, Jul 2008].
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Alpha-2-Macroglobulin (A2M) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | IHC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P01023 |
| Gene ID | 2 |
| NCBI Accession | NP_000005.2 |
| Alias | A2MD,CPAMD5,FWP007,S863-7 |
| Background | Antibody anti-A2M |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
Alpha-2-Macroglobulin (A2M) is a large plasma glycoprotein involved in various physiological processes, including immune response regulation, inflammation modulation, and protease inhibition.α-2 macroglobulin (α-2 M) is an inhibitor of matrix metalloproteinases (MMPs). This role occurs when other inhibitors of MMPs, such as tissue inhibitors of matrix metalloproteinases [TIMPs], are deficient.
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