Aldolase B, Fructose Bisphosphate (ALDOB) Antibody
221€ (50 µg)
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935106861
info@markelab.com
name
Aldolase B, Fructose Bisphosphate (ALDOB) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx328604
tested applications
ELISA, WB, IHC
Description
ALDOB Antibody is a Rabbit Polyclonal against ALDOB.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Aldolase B, Fructose Bisphosphate (ALDOB) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1/20000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/300. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P05062 |
| Gene ID | 229 |
| Alias | ALDOB,ALDB |
| Background | Antibody anti-ALDOB |
| Status | RUO |
Descripción
ALDOB is a liver-specific isoform of fructose-bisphosphate aldolase that primarily participates in fructose metabolism. It catalyzes the breakdown of fructose-1,6-bisphosphate and fructose-1-phosphate into dihydroxyacetone phosphate and glyceraldehyde, which are intermediates in glycolysis and gluconeogenesis. ALDOB is highly expressed in the liver, kidney, and small intestine. Mutations in ALDOB result in hereditary fructose intolerance (HFI), an autosomal recessive disorder characterized by the toxic accumulation of fructose-1-phosphate, leading to hypoglycemia, hepatomegaly, and renal dysfunction. ALDOB’s critical role in fructose metabolism highlights its importance in dietary sugar processing and maintaining energy balance.
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