Alanyl-tRNA Synthetase Domain Containing 1 (AARSD1) Antibody
364€ (100 µg)
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935106861
info@markelab.com
name
Alanyl-tRNA Synthetase Domain Containing 1 (AARSD1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx230023
tested applications
ELISA, WB
Description
AARSD1 Antibody is a Rabbit Polyclonal against AARSD1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Alanyl-tRNA Synthetase Domain Containing 1 (AARSD1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/5000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9BTE6 |
| Gene ID | 100885850 |
| OMIM | 613212 |
| Alias | AlaXp |
| Background | Antibody anti-AARSD1 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
Alanyl-tRNA Synthetase Domain Containing 1 (AARSD1) is a mitochondrial protein involved in the synthesis of alanyl-tRNA, which is essential for the translation of mitochondrial-encoded proteins. It catalyzes the attachment of alanine to its corresponding tRNA, ensuring proper protein synthesis for mitochondrial function and energy production. AARSD1 is critical for mitochondrial biogenesis and oxidative phosphorylation, and mutations in the AARSD1 gene can lead to mitochondrial dysfunction, resulting in metabolic disorders, neurodegenerative diseases, or myopathies. Emerging studies suggest that AARSD1 also plays a role in cellular stress responses and may influence processes such as apoptosis and adaptive mitochondrial dynamics.
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