Alanine Glyoxylate Aminotransferase 2 (AGXT2) Antibody Pair
1170€ (5 × 96 tests)
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name
Alanine Glyoxylate Aminotransferase 2 (AGXT2) Antibody Pair
category
Antibody Pairs
provider
Abbexa
reference
abx370900
tested applications
ELISA
Description
Alanine Glyoxylate Aminotransferase 2 (AGXT2) Antibody Pair for use in Sandwich ELISA assay development. This antibody pair contains: Detection: 50 µg Capture: 200 µg Standard: 5 µg
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Antibody Pairs |
| Immunogen Target | Alanine Glyoxylate Aminotransferase 2 (AGXT2) |
| Host | Capture Host: Rabbit Detection Host: Rabbit |
| Reactivity | Human |
| Assay Data | Sandwich |
| Assay Type | Capture Antibody: 0.5 mg/ml Biotin-Conjugated Detection Antibody: 0.2 mg/ml Reconstitute the standard with Standard Diluent. The volume, and therefore standard concentration, should be determined by the end user. For a standard curve range of 78 pg/ml - 5000 pg/ml, a reconstitution volume of 1 ml is recommended. |
| Test Range | 78 pg/ml - 5000 pg/ml |
| Recommended Dilution | Dilute the Capture Antibody 125-fold with Coating Buffer. Dilute the Biotin-Conjugated Detection Antibody 200-fold with Detection Antibody Diluent. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Capture Clonality: Polyclonal Detection Clonality: Polyclonal |
| Conjugation | Biotin |
| Size 1 | 5 × 96 tests |
| Size 2 | 10 × 96 tests |
| Form | Standard form: Lyophilized Capture Ab: Liquid Detection Ab: Liquid |
| Tested Applications | ELISA |
| Buffer | The Capture and Detection Antibody both contain 0.1% sodium azide. |
| Availability | Shipped within 5-20 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | AGXT2, AGT3 |
| Background | Antibody pair for AGXT2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Alanine-glyoxylate aminotransferase 2 (AGXT2) is a mitochondrial enzyme that participates in the metabolism of amino acids, including the reversible conversion of glyoxylate and alanine to pyruvate and glycine. AGXT2 plays a role in cardiovascular health by metabolizing dimethylarginines, including asymmetric dimethylarginine (ADMA), an inhibitor of nitric oxide synthase and a biomarker for cardiovascular diseases. By reducing ADMA levels, AGXT2 contributes to the regulation of nitric oxide production and endothelial function. Dysregulation of AGXT2 is implicated in hypertension, atherosclerosis, and metabolic syndromes. In addition, AGXT2's role in glyoxylate metabolism links it to oxalate production, suggesting potential contributions to kidney stone formation and renal dysfunction in certain pathological contexts.
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