AIMP1 Protein

234€ (1 µg)
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name
AIMP1 Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx263242
tested applications
SDS-PAGE
Description
Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 Protein is a recombinant cytokine.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Proteins and Peptides |
Immunogen Target | AIMP1 |
Origin | Human |
Conjugation | Unconjugated |
Expression | Recombinant |
Purity | > 85% (SDS-PAGE) |
Size 1 | 1 µg |
Size 2 | 5 µg |
Size 3 | 50 µg |
Form | Liquid |
Tested Applications | SDS-PAGE |
Availability | Shipped within 5-10 working days. |
Dry Ice | No |
UniProt ID | Q12904 |
Alias | p43,HLD3,EMAP2,SCYE1,EMAPII |
Background | Protein AIMP1 |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
AIMP1, also known as EMAP II (Endothelial Monocyte-Activating Polypeptide II), is a multifunctional protein that acts as a core component of the multi-aminoacyl-tRNA synthetase complex (MSC), which is essential for protein synthesis. It interacts with various aminoacyl-tRNA synthetases to maintain the stability and functionality of the complex. Beyond its role in translation, AIMP1 has extracellular signaling functions, particularly in modulating immune responses and angiogenesis. When secreted, AIMP1 functions as a cytokine that activates monocytes and endothelial cells, contributing to inflammatory responses and tissue repair. It is also involved in apoptosis, cellular stress responses, and tumor suppression. Dysregulation of AIMP1 is associated with cancer progression, inflammatory diseases, and autoimmune disorders, highlighting its dual roles in intracellular protein synthesis and extracellular signaling.
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