AGE (Advanced glycation end-product) ELISA Kit
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Name
AGE (Advanced glycation end-product) ELISA Kit
Category
ELISA Kits
Provider
FineTest
Reference
EU0406
Tested Applications
ELISA
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Reactivity | Universal |
| Detection Method | Colorimetric |
| Assay Data | 2 hours |
| Assay Type | Competitive ELISA, Coated with Antigen |
| Test Range | 62.5-4000ng/ml |
| Sensitivity | 37.5ng/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| Alias | AGE |
| Background | Elisa kits for AGE |
| Status | RUO |
Background
Advanced Glycation End Products (AGEs) are a diverse group of molecules formed through the non-enzymatic reaction of reducing sugars with proteins, lipids, or nucleic acids in a process called glycation. AGEs accumulate under conditions of oxidative stress and hyperglycemia, particularly in diseases like diabetes mellitus, where they are formed in excess. They are commonly found in long-lived proteins such as collagen and elastin, contributing to tissue stiffness and organ dysfunction. AGEs can crosslink proteins, disrupt cellular signaling, and impair extracellular matrix structure. They are also known to interact with specific receptors, such as the AGE receptor (AGER), activating inflammatory and oxidative pathways that lead to chronic conditions such as cardiovascular disease, kidney damage, and neurodegeneration. AGEs are considered major contributors to aging and the progression of age-related diseases, making them significant biomarkers and therapeutic targets.
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