Adrenomedullin 2 (ADM2) Antibody
364€ (100 µg)
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935106861
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name
Adrenomedullin 2 (ADM2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx230173
tested applications
ELISA, IHC
Description
ADM2 Antibody is a Rabbit Polyclonal against ADM2.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Adrenomedullin 2 (ADM2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q7Z4H4 |
| Alias | AM2 |
| Background | Antibody anti-ADM2 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
Adrenomedullin 2 (ADM2), also known as Intermedin, is a member of the calcitonin gene-related peptide (CGRP) family. This peptide is widely expressed in various tissues, including the brain, cardiovascular system, kidneys, and gastrointestinal tract. ADM2 exerts its biological effects through the calcitonin receptor-like receptor (CLR) in association with receptor activity-modifying proteins (RAMPs). It plays a vital role in maintaining vascular tone, promoting angiogenesis, and regulating fluid and electrolyte balance. ADM2 also has neuroprotective, cardioprotective, and anti-inflammatory properties. Dysregulation of ADM2 signaling has been implicated in conditions such as hypertension, heart failure, and metabolic disorders, highlighting its therapeutic potential in these diseases.
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