Adrenomedullin 2 (ADM2) Antibody
357.5€ (100 µg)
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935106861
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name
Adrenomedullin 2 (ADM2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx037694
tested applications
ELISA, IHC
Description
Rabbit Polyclonal against the ADM2 protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Adrenomedullin 2 (ADM2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, IHC |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q7Z4H4 |
| Alias | AM2 |
| Background | Antibody anti-ADM2 |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
Adrenomedullin 2 (ADM2), also known as Intermedin, is a member of the calcitonin gene-related peptide (CGRP) family. This peptide is widely expressed in various tissues, including the brain, cardiovascular system, kidneys, and gastrointestinal tract. ADM2 exerts its biological effects through the calcitonin receptor-like receptor (CLR) in association with receptor activity-modifying proteins (RAMPs). It plays a vital role in maintaining vascular tone, promoting angiogenesis, and regulating fluid and electrolyte balance. ADM2 also has neuroprotective, cardioprotective, and anti-inflammatory properties. Dysregulation of ADM2 signaling has been implicated in conditions such as hypertension, heart failure, and metabolic disorders, highlighting its therapeutic potential in these diseases.
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