ADP Ribosyltransferase 1 (ART1) Antibody

312€ (60 µl)
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935106861
info@markelab.com
name
ADP Ribosyltransferase 1 (ART1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx136013
tested applications
IHC, IF/ICC
Description
ART1 Antibody is a Rabbit Polyclonal against ART1.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | ADP Ribosyltransferase 1 (ART1) |
Host | Rabbit |
Reactivity | Human, Mouse |
Recommended Dilution | IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified by affinity chromatography. |
Size 1 | 60 µl |
Size 2 | 120 µl |
Size 3 | 200 µl |
Form | Liquid |
Tested Applications | IHC, IF/ICC |
Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | P52961 |
Gene ID | 417 |
NCBI Accession | NP_004305.2 |
Alias | GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1,RT6,ART2,ARTC1,CD296,ADP-ribosyltransferase C2 and C3 toxin-like 1,Mono(ADP-ribosyl)transferase 1 |
Background | Antibody anti-ART1 |
Status | RUO |
Note | Concentration: 1 mg/ml - |
Descripción
ADP-ribosyltransferase 1 (ART1) is an enzyme that belongs to the ART superfamily of proteins, which catalyze the transfer of ADP-ribose from NAD+ (nicotinamide adenine dinucleotide) to target proteins, a process known as mono-ADP-ribosylation. This post-translational modification alters the function of target proteins, influencing various cellular processes, including signal transduction, immune responses, cell differentiation, and apoptosis. ART1 is primarily expressed in immune cells and skeletal muscle tissues and has been associated with immune modulation, inflammatory responses, and cell adhesion. As ART1 modifies proteins by adding an ADP-ribose moiety, it has significant roles in regulating interactions between cells and in modulating the immune response, making it an area of interest in immunology and cancer research.
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